Inactivation of Herpes Simplex Virus by Concanavalin A

The Inactivation of Herpes Simplex Virus by Phosphatase Enzymes

Tissue phosphatases which are present in virus suspensions were found to contribute in considerable measure to the inactivation of herpes simplex virus. Phosphatase inhibitors and phosphatase substrates have been found to prolong the survival of the virus. Exogenous phosphatases, both acid and alkaline, have been demonstrated to bring about the loss of infectivity of suspensions of this virus.

Serodiagnosis of Herpes Simplex Virus-I Infections by a Prepared Antigen

Separation of Herpes simplex virus-induced antigens by Concanavalin A affinity chromatography.

Biologically active herpes simplex virus (HSV)-induced antigens were selectively removed from extracts of infected BHK cells by affinity chromatography by utilizing an insoluble form of concanavalin A (Con A). Soluble extracts of (3)H-glucosamine-labeled, HSV-infected cells were absorbed to a Con A column. Bound material was eluted with alpha-methyl-d-mannoside (alphaMM) and NaCl. The specific ...

Herpes Simplex Virus Meningoencephalitis in A Methamphetamin User

Herpes Simplex Virus and Langerhans Cell Histiocytosis

Background and objective: Langerhans cell histiocytosis (LCH) is a rare histiocytic proliferative disorder of unknown etiology and mainly affects young children. The histological feature is granuloma-like proliferation of langerhans-type dendritic cells. Although the possible role of viruses such as Epstein-Barr virus (EBV, Human Herpes virus -4</...